A 60 year old male with delayed responsiveness and scrotal swelling

 CBBLE UDHC SIMILAR CASES


CASE OF  
A- DKA SECONDARY TO ? FOURNIER'S GANGRENE. 

 15 February 22


THIS IS AN ONLINE E LOG BOOK TO DISCUSS OUR PATIENT'S DE - IDENTIFIED HEALTH DATA SHARED AFTER TAKING HIS / HER /GUARDIAN'S SIGNED INFORMED CONSENT .HERE WE DISCUSS OUR INDIVIDUAL PATIENT'S PROBLEMS THROUGH SERIES OF INPUTS FROM AVAILABLE GLOBAL ONLINE COMMUNITY OF EXPERTS WITH AN AIM TO SOLVE THOSE CLINICAL PROBLEMS WITH COLLECTIVE CURRENT BEST EVIDENCE BASED INPUT 

A 60 year old male ,teacher by occupation, was brought to casualty in a drowsy state since yesterday, fever since 2 days , vomitings since yesterday
HOPI:- Patient was apparently asymptomatic 30 years back then he had fever, following which he took some medication at local health centre after which patient had ? Allergic reactions and since then he is feeling that something is happening to him for which the patient consulted a psychiatrist and got treated . Since then the patient was on Tab. Fluoxetine.
H/o giddiness 25 years back for which patient went to a local hospital and got diagnosed with hypertension and was started on Tab. ATEN-AM 50/5 mg OD.
During a routine health check up 20 years back , patient was diagnosed with Diabetes mellitus and started using Tab. Glimi M1 OD
H/o gradual painless diminision of vision 10-15 years back for which the patient consulted an ophthalmologist and was diagnosed with cataract.
Patient retired 2 years back, and stopped taking DM and HTN medication as he was feeling well since then , but kept using irregularly
One month back , his daughter committed suicide and expired following which he got disturbed psychologically and started excess consumption of alcohol.
Patient now presented with h/o fever since 2 days, low grade associated with 20 episodes of vomitings since yesterday, non projectile, non bilious, with food particles as content. Not associated with pain abdomen, no SOB, associated with generalized weakness.

Past history:-
Patient is a k/c/o DM since 20 years and is in Tab. Glimi M1 OD
K/c/o HTN since 25 years and is on Tab. ATEN- AM 50/5 mg OD

GENERAL EXAMINATION:-
Patient is slightly drowsy, coherent and cooperative
Icterus present



No signs of pallor, Cyanosis, lymphadenopathy, edema
Vitals:- 
Temp:- Afebrile
BP:- 100/80 mmhg
PR:- 71 bpm
RR:- 22 cpm
Spo2- :- 99% at room air.
GRBS- High.
SYSTEMIC EXAMINATION:- 
CVS- S1, S2 heard, no murmurs
RS - Bilateral air entry present, NVBS heard.
Per abdomen:- Obese , non tender, scrotal abscess present ?fournire's gangrene
CNS:- NAD


                        Before debridement

                       After debridement

Surgery referral done:-
-3x2 CMS necrotic patch over scrotum
-Pus discharge present
-Induration present around scrotal abscess.
Sent for swab and pus culture and sensitivity.
? Fournier's gangrene


Investigations:- 
CBP:- Hb- 10.1 g/dl
TLC- 28,000 cells/mm3
Platelets-3.64

RFT:- 
Urea-101 mg/dl
Creatinine- 1.4 mg/dl
Na- 128 meq/litre
K+ - 4.7 mEq/L
Cl- 90 mEq /L

LFT:-
TB - 4.63
DB -0.17
AST -33
ALT- 16
ALP -333
TP- 6.0
Alb- 2.6

USG ABDOMEN AND PELVIS:-
Impression:- Grade 1 prostatomegaly
Bilateral renal calculi.

ECG 
Chest x-ray



Serology- negative
RTPCR - Negative

PT- 18
INR -1.3
APTT - 37 secs
BT - 2 mins 30 secs
CT - 5 mins

TREATMENT:-

1) INJ. MAGNEX FORTE 1.5 gm IV/ BD
2) INJ. CLINDAMYCIN 600 mg IV TID
3) IVF NS @ 150ml/ hr
4) INJ. HAI 40 units in 39 ml NS IV @6 ml/hr >/< according to GRBS
5) INJ. NORADRENALINE 1 Amp in 49 ml NS @ 6 ml/hr >/<  to maintain MAP >/= 65mmhg
6) INJ. PAN 40 MG IV OD
7) INJ. ZOFER 4 mg IV / TID
8) INJ. THIAMINE 1 amp in 100 ml NS IV OD
9) BP/ PR/ Spo2 / GRBS monitoring every hourly
10)Strict input / output charting

SOAP NOTES DAY 2



S - pain at surgical site decreased, delayed responsiveness decreased 


O - pt is C/c/c

Oriented to time, place, person

Bp - 110/70 mmHg on NA @ 5ml/hr

PR 80bpm

RR 20cpm

Spo2 - 98% on RA

Grbs:- 95 mg/dl

CVS - S1 S2 HEARD, no murmurs

RS - BAE present, NVBS

P/A - soft and nontender, bowel sounds present, scrotal abcess (? Fournier gangrene) present.

CNS - NAD

Abg done at 7:45 am:-

pH - 7.51

PCO2 - 20.4

PO2 -90.8

Hco3 - 20.5 

Anion gap- 16.6

Urine for ketone bodies- negative.


A - DKA with septic shock secondary to Fournier gangrene with depression


P- taper and stop insulin & NorAdrenaline infusion

Psychiatry referral.


16/2/22

FBS - 127 mg/dl

CUE- Alb : nil ; Sugars +

Hemogram- Hb - 10.4 g/dl ;TLC - 22,700 

N/L/E/M :- 86/07/01/06

Plt- 3.27


LFT:-

TB 0.63

DB 0.13

AST 29

ALT 12

ALP 220

TP 5.4

Alb- 2.5


Serum creatinine 0.8 mg/dl


Serum electrolytes:/

Na - 132

Potassium - 3.1

Cl - 99


SOAP NOTES DAY 3:-


S - pain at surgical site decreased, delayed responsiveness decreased . Patient is feeling symptomatically better.


O - pt c/c/c

Oriented to time, place, person

Bp - 130/70 mmHg

PR -80bpm

RR -20cpm

Spo2 - 98% on RA

CVS - S1 S2 HEARD, no murmurs

RS - BAE present, NVBS

P/A - soft and nontender, bowel sounds present, scrotal abcess (? Fournier gangrene present)  

CNS - NAD



A - DKA with septic shock secondary to Fournier gangrene 

Alcohol harmful use ?psychosis under remission.


P-

1) INJ. MAGNEX FORTE 1.5 gm IV/ BD

2) INJ. CLINDAMYCIN 600 mg IV TID

3) IVF NS @ 100ml/ hr

4)INJ. PAN 40 MG IV OD

5)INJ. ZOFER SOS

6)INJ. THIAMINE 1 amp in 100 ml NS IV OD

7)BP/ PR/ Spo2 / GRBS monitoring every hourly

8)Strict input / output chart

9)INJ . KCL 2 amp in 500 ml NS over 4 hrs.

10)TAB. PREGABALIN 75 mg H/S

11)SITZ BATH TID

12) Inj. HAI 40U in 39ml NS IV @ 2ml/hr ( stopped today morning and bridged with SC insulin)

                                      Patient on sitz bath

17/2/22

CBP:- Hb- 9.8

TLC - 13,800

Plt- 3.1


RFT :- UREA- 11

Creatinine- 0.8

Na- 137

K - 2.9

Cl- 93


LFT 

TB 0.63

DB 0.17

AST 19

ALT 09

ALP 201

TP 5.1

ALB 2.39


ECG 


18/2/22:-
Hypokalemic changes reverted back in ECG
serum K+ correction from 2.9 to 3.5

serum K+ 3.5 

Blood urea - 13 mg/dl

Hb - 9.2 g/dl

Serum creatinine- 0.8 mg/dl

TLC- 9,200 cells/mm3






DATE

WBC (cells/mm3)

15/2/22

28,000

16/2/22

22,700

17/2/22

13,800

18/2/22

9,200


DATE

SERUM K+(mEq/l)

15/2/22

4.7

16/2/22

3.1

17/2/22

3.5

18/2/22

3.5


20/2/22


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